Histopathological Analysis of Nervous Tissue in Rabid Buffaloes
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Abstract
In the present study, histomorphological alterations in nervous tissue of 28 buffaloes were studied for diagnosis of rabies virus lesions. Sensitivity of histomorphological alterations was compared with immunofluorescence (FAT). On the basis of Negri body detection and histomorphological alterations rabies was confirmed in 17 (62.96%) cases. Sensitivity of histomorphological study as compared with FAT was found to be 100%. Quantitative assessments of histomorphological alterations were Gliosis, Neuronal degeneration, Congestion, Perivascular cuffing, Satellitosis, Hemorrhages, Edema, Meningitis, Neuronophagia, Babes’ nodules, Spongiosis and Vacuolation in Negri bodies.
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